Delivery Strategies for Periodic Blood Products Supplies
نویسندگان
چکیده
We introduce a real-life problem faced by the blood bank of the Austrian Red Cross for Eastern Austria: how to cost-effectively organize the periodic delivery of blood products to Austrian hospitals. We present various solution approaches, based on integer programming and variable neighborhood search, and empirically evaluate their performance. Moreover, we study the potential value of switching from the current vendee managed inventory set up to a vendor managed inventory system.
منابع مشابه
Expert Consensus Statement on achieving self-sufficiency in safe blood and blood products, based on voluntary non-remunerated blood donation (VNRBD).
All countries face challenges in making sufficient supplies of blood and blood products available and sustainable, while also ensuring the quality and safety of these products in the face of known and emerging threats to public health. Since 1975, the World Health Assembly (WHA) has highlighted the global need for blood safety and availability. WHA resolutions 63·12, 58·13 and 28·72, The Melbou...
متن کاملA particle swarm optimization method for periodic vehicle routing problem with pickup and delivery in transportation
In this article, multiple-product PVRP with pickup and delivery that is used widely in goods distribution or other service companies, especially by railways, was introduced. A mathematical formulation was provided for this problem. Each product had a set of vehicles which could carry the product and pickup and delivery could simultaneously occur. To solve the problem, two meta-heuristic methods...
متن کاملCell penetrating and transytosing peptides: powerful strategies for oral insulin delivery
Insulin is essential for type 1 and advanced type 2 diabetes to maintain blood glucose levels and increase the patient’s longevity. Frequent subcutaneous insulin injections are usually associated with pain, local tissue necrosis, infection and nerve damage. Recently, a number of new delivery methods such as oral insulin delivery have been developed to overcome these limitations and increase pa...
متن کاملTime-dependent behavior of interstitial fluid pressure in solid tumors: implications for drug delivery.
Elevated interstitial fluid pressure (IFP) may constitute a significant physiological barrier to drug delivery in solid tumors. Strategies for overcoming this barrier have not been developed to date. To identify and characterize various mechanisms regulating IFP and to develop strategies for overcoming the IFP barrier, we modeled the tumor as a poroelastic solid. We used this model to simulate ...
متن کاملLessons learnt from sexual and reproductive health and HIV linkages for multipurpose prevention technology service delivery.
Provision of comprehensive sexual and reproductive health (SRH) services that meet the complex and diverse needs of women, in particular, within resource-constrained settings, is often exacerbated by separate and uncoordinated reproductive health (RH) and HIV policies and programmes. A Rapid Assessment Tool for Sexual and Reproductive Health and HIV Linkages was developed to assess bi-direction...
متن کامل